Adrenal and Pituitary SIG

Date: January 12, 2024 

Time: 9:00 to 10:30 AM ET 

Moderator:

Ismat Shafiq, MD
Associate Professor of Medicine and Neurosurgery
University of Rochester School of Medicine and Dentistry 

Speakers:  

Márta Korbonits, MD, PhD, DSc, FRCP 
Professor of Endocrinology and Metabolism 
Barts and the London School of Medicine and Dentistry,  
Queen Mary University of London 

Pedro Marques, MD, PhD 
Pituitary Tumor Unit, Endocrinology Department, Hospital CUF Descobertas, Lisbon 
Faculdade de Medicina, Universidade Católica Portuguesa, Lisbon, Portugal 

Description:  

Join our Adrenal Pituitary Special Interest Group for an insightful Webinar focusing on the nuances of the Growth Hormone (GH) axis. While clinical diagnosis of Acromegaly may seem straightforward, this webinar delves into situations where the patient exhibits acromegalic features despite normal growth hormone function. Similarly, we explore the complexities of biochemical testing for acromegaly, where variations in GH and Insulin-like growth-factor-1(IGF-1) levels may arise from physiologic, pathologic, and pharmacologic factors. Participate in this webinar to gain valuable knowledge that goes beyond the typical diagnostic criteria and enhance your ability to navigate the subtleties in the clinical and biochemical landscape of acromegalic presentations.  

Learning Objectives:

1. Gain insights into the conditions that clinically resemble acromegaly.
2. Address Challenges and nuances in the diagnosis and management of conditions that mimic acromegaly. 
3. Understanding the discrepancy between GH and IGF-1 due to pharmacologic, physiologic, and pathologic causes.

Adrenocortical Carcinoma: The Latest Pre-Clinical and Clinical Updates

February 17, 2023

Learning Objectives

1. Review the essential clinical features of adrenocortical carcinoma (ACC)
2. Discuss the translational research in ACC 
3. Summarize treatment options for localized and advanced ACC

Speakers

Mouhammed Habra, Md, FACP, FACE 
Professor 
Chief, Section of Endocrine Neoplasia
Department of Endocrine Neoplasia and Hormonal Disorders 
The University of Texas MD Anderson Cancer Center

Katja Kiseljak-Vassiliades, DO 
Associate Professor 
University of Colorado School of Medicine
Anschutz Medical Campus
Department of Internal Medicine
Division of Endocrinology, Metabolism and Diabetes

Moderator
Inga Harbuz Miller, MD
Assistant Professor
University of Rochester 

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Adrenal Pituitary Special Interest Group held a September 23, 2022 webinar on the genetics of pituitary tumors. Gain knowledge of the mutations in patients with pituitary tumors and know when to consider genetic screening in various clinical scenarios.

Speaker:
Albert Beckers, MD, PhD
Chief of the Department of Endocrinology
University Hospital Centre, Liège
Professor
University of Liège

Moderators:
Niki Karavitaki, PhD, FRCP
Clinical Associate Professor
University of Birmingham
Honorary Consultant Endocrinologist
Queen Elizabeth Hospital Birmingham

Ismat Shafiq, MD
Endocrinologist,
Associate Professor
University of Rochester Medical Center

Learning Objectives:

1. Understand the genetic landscape in pituitary tumors.
2. Recognize the indications for genetic testing in patients with pituitary tumors.
3. Gain knowledge on the follow-up of patients with positive genetic testing.

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Working with Big Data

This event was held May 9, 2022, 11 AM-12 PM ET. 

Speakers:
Nestoras Mathioudakis, MD, MHS Co-Medical Director, Associate Professor of Medicine, MHM Diabetes Prevention and Education Program, Johns Hopkins University of Medicine
Roberto Salvatori, MD Professor of Medicine and Medical Director Johns Hopkins University School of Medicine
Neelanjan Mukherjee, PhD Assistant Professor University of Colorado Anschutz Medical Center

Learning Objectives:

1. To describe the process of conducting machine learning research using large electronic health record data.
2. To recognize common types of machine learning algorithms used in healthcare and to understand how to compare performance of different models.
3. To review machine learning research and potential applications in the field of endocrinology. 

Challenges in the Diagnosis of Cushing’s Syndrome Webinar 

Speakers: John Newell Price, PhD, FRCP; and Roberto Salvatori, MD

Moderators: Niki Karavitaki, PhD, FRCP; and Ismat Shafiq, MD 

The Adrenal and Pituitary Special Interest Group held a webinar on the diagnostic challenges associated with Cushing’s Syndrome.

Learning Objectives:

• Understand the key clinical manifestations of Cushing’s syndrome prompting diagnostic tests.
• Understand the diagnostic value and pitfalls of the tests used in confirming Cushing’s syndrome.
• Gain knowledge on the biochemical approaches used to identify the etiology of Cushing’s syndrome. 

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Networking Event - Adapting in a Pandemic:  Challenges and Lessons Learned Networking Event at ENDO 2021 

Co-Chairs: Lauren Fishbein, MD, PhD, Niki Karavitaki, MSc, PhD, FRCP 

The Adrenal/Pituitary Special Interest Group arranged small group discussions during ENDO 2021 on the challenging and illuminating experiences we have all shared since the outbreak of COVID-19. This event featured networking breakout sessions based on clinical and basic science interests. Attendees with adrenal and pituitary expertise had the opportunity to discuss the new normal during the pandemic. Clinical discussions covered topics such as adapting to telehealth, tele-education, and virtual labs. The research discussion highlighted issues including adapting to research life when facing new challenges including closed labs, limited opening of labs and clinical trials, writing papers/grants remotely, and teaching in the virtual world. In addition to considerations of the new difficulties presented, we also shared lessons learned and positive byproducts of working virtually.

Pituitary Microenvironment: The Science and the Clinical Implications

The Adrenal and Pituitary Special Interest Group held a webinar on the Pituitary Microenvironment: The Science and the Clinical Implications. The webinar featured Marta Korbonits, MD, PhD; Gerald Raverot, MD, PhD; Lauren Fishbein, MD, PhD; and Roberto Salvatori, MD.

Learning Objectives

• Impact of the microenvironment in pituitary tumor behavior.
• Therapeutic perspectives targeting the pituitary tumor microenvironment.
• Mice models for in vivo studies will be discussed.

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Adrenal and Pituitary: Ask the Experts Webinar

This webinar featured experts in the field of Adrenal and Pituitary.  

Moderators:

Ricardo Correa, MD, EdD
Program Director for Endocrinology
University of Arizona College of Medicine-Phoenix and Phoenix VAMC

Ismat Shafiq, MD
Associate Professor
University of Rochester

Speakers: Mark Molitch, MD
Professor Emeritus
Northwestern University Feinberg School of Medicine

Valeria de Miguel, MD
Endocrinologist
Hospital Italiano

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The Paper That Changed My Practice

This webinar promoted critical review of published literature on adrenal and pituitary conditions and highlight publications which, according to the presenters, have impacted their clinical practice. It also enhanced knowledge and generated productive discussion on the topics covered, including:

• The cardiovascular risk and mortality in patients with adrenal incidentaloma which is non-secreting or is associated with subclinical Cushing's;
• The significance of ARMC5 gene defects in primary aldosteronism in clinical practice;
• The consequences of Cushing's disease on long-term mortality and adjusting the approach in the long-term follow-up of these patients; and
• The management options of thyrotropin-secreting pituitary adenomas.

Moderator: Lauren Fishbein, MD, PhD
Assistant Professor
University of Colorado School of Medicine

Speakers:

Ricardo Correa, MD, EdD
Program Director for Endocrinology
University of Arizona College of Medicine-Phoenix and Phoenix VAMC

Niki Karavitaki, MSc, PhD, FRCP
Senior Clinical Lecturer in Endocrinology
Institute of Metabolism and Systems Research (IMSR)

Ismat Shafiq, MD
Associate Professor
University of Rochester

Sona Sharma, MD
Faculty/Clinical Instructor
Duke University

Hormone Measurements: An Update for the Clinical Endocrinologist 

• Hershel Raff, PhD, FAAAS, FAPS, Professor of Medicine, Surgery, and Physiology, Medical College of Wisconsin & Advocate Aurora Research Institute 
• Rashmi Mullur, MD, Associate Professor, David Geffen School of Medicine at UCLA
• Rachel Webster, BSc (Hons) PhD FRCPath, Consultant Clinical Scientist, Trust Lead Scientist for Life Sciences, University of Birmingham 

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Clinical Vignettes to Ask the Expert: Unique Cases of Pheochromocytoma/Paraganglioma

The Adrenal Pituitary SIG held a dialogue about unique cases of pheochromocytoma and paraganglioma. In this open discussion, endocrinology fellows presented complex cases of pheochromocytoma and paraganglioma and receive analysis and treatment recommendations from subject-matter experts.

Learning Objectives

• Identify complex, atypical presentations of pheochromocytoma and learn the screening measures needed in these cases.
• Determine the best options for case management and treatment for patients with ACTH producing pheochromocytoma.
• Identify treatment options for metastatic and unresectable paragangliomas.

Expert Speaker: Karel Pacak, DSc, MD, PhD, Senior Investigator, NIH Eunice Kennedy Shriver National Institute of Child Health and Human Development

Expert Speaker: Lauren Fishbein, MD, PhD, MTR, Assistant Professor in Medicine, University of Colorado School of Medicine Case

Presenter: Yumiko Esaki, MD, Internal Medicine and Pediatrics Resident, University of Rochester School of Medicine and Dentistry

Case Presenter: John Webster, DO, Endocrinology Fellow, University of Arizona College of Medicine

Moderator: Ricardo Correa, MD, EdD, University of Arizona, College of Medicine, Phoenix

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